Analyzing High-Speed Video Images to Quantify the Performance of Innovative Drug Deli

[labfans]

The AIR pulmonary drug delivery technology being developed at Alkermes provides targeted delivery of small-molecule or macromolecule drug particles from an easy-to-use, capsule-based, hand-held inhaler. When the patient inhales through the mouthpiece, air is drawn into the aerosolization chamber, agitating a capsule and releasing dry-powder medicine for systemic or local delivery to the lungs. To optimize future inhaler designs, Alkermes developed a test method to understand the behavior of the capsule under a range of operating conditions—for example, a range of air flows representing patients of differing age and size.

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